Searchable abstracts of presentations at key conferences in endocrinology

ea0041gp49 | Bone & Calcium Homeostasis (1) | ECE2016

Longitudinal changes in maternal 25(OH)D3 and free 25(OH)D, vitamin D binding protein and the relationship with cord vitamin D metabolites

Hey Felicity , Schoenmakers Inez , Assar Shima , Moore Sophie E. , Prentice Ann , Jones Kerry S.

Low maternal vitamin D (VD) status is associated with adverse fetal development. However gestational changes in VD metabolites and their relationship with cord concentrations are unclear.The plasma concentration of 25-hydroxyvitamin D3 (25(OH)D3) was measured using UPLC-MS/MS, and free 25(OH)D and vitamin D binding protein (DBP) concentrations were measured by ELISA. Plasma samples were collected longitudinally from women resident i...

ea0037ep234 | Calcium and Vitamin D metabolism | ECE2015

The effects of maternal iron status on infant fibroblast growth factor-23 and mineral metabolism

Braithwaite Vickie S , Prentice Ann , Darboe Momodou K , Prentice Andrew M , Moore Sophie E

Fibroblast growth factor-23 (FGF23), a phosphate-regulating hormone is elevated in hypophosphataemic syndromes and is a predictor of mortality in patients with kidney disease. Recent findings demonstrate iron deficiency as a potential mediator of FGF23 expression and murine studies have shown in utero effects of maternal iron deficiency on FGF23 and phosphate (P) metabolism and bone formation (Clinkenbeard, JBMR, 2013).The aim of the cu...